Skip to main content

Table 1 Correlation of clinicopathologic characteristics with SIRT1 protein, VEGF-C protein, LVD and LVI

From: SIRT1 expression is associated with lymphangiogenesis, lymphovascular invasion and prognosis in pN0 esophageal squamous cell carcinoma

Variables SIRT1 P VEGF-C P LVD P LVI P
Negative (n = 111) Positive (n = 95) Negative (n = 99) Positive (n = 107) Low (n = 123) High (n = 83) Negative (n = 135) Positive (n = 71)
Gender    0.975    0.516    0.171    0.897
  Male 82 70   71 81   95 57   100 52  
  Female 29 25   28 26   28 26   35 19  
Age (year)    0.697    0.786    0.842    0.327
  <50 30 28   27 31   34 24   35 23  
  ≥50 81 67   72 76   89 59   100 48  
Weight loss (kg)    0.205    0.834    0.940    0.239
  <2.5 67 49   55 61   69 47   80 36  
  ≥2.5 44 46   44 46   54 36   55 35  
Length of tumor (cm)    0.654    0.492    0.991    0.980
  <3 45 43   45 43   53 35   58 30  
  3-5 55 41   42 54   57 39   63 33  
  >5 11 11   12 10   13 9   14 8  
Differentiation    0.070    0.125    0.294    0.027
  Well 27 13   25 15   28 12   30 10  
  Moderate 56 62   53 65   69 49   81 37  
  Poor 28 20   21 27   26 22   24 24  
Tumor location    0.227    0.083    0.765    0.370
  Upper 17 8   17 8   16 9   19 6  
  Middle 56 57   49 64   65 48   70 43  
  Lower 38 30   33 35   42 26   46 22  
T status    <0.001    0.025    0.439    0.036
  T1 26 7   23 10   23 10   26 7  
  T2 63 47   48 62   64 46   75 35  
  T3 22 41   28 35   36 27   34 29  
Stage    0.001    0.001    0.069    0.039
  I 30 13   31 12   32 11   35 8  
  IIa 47 28   35 40   44 31   48 27  
  IIb 34 54   33 55   47 41   52 36  
  1. LVD: lymphatic microvessel density.
  2. LVI: lymphovascular invasion.