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Table 1 Classification of epigenetic modifiers

From: Epigenetic regulation in cancer progression

Class Enzymes
Histone Acetyltransferases (HATs) ELP3/KAT9 PCAF/KAT2B MORF/MYST4/KAT6B
GTF3C4 CBP/KAT3A HBO1/MYST2/KAT7
HAT3 p300/KAT3B MOF/MYST1/KAT8
HAT1/KAT1 Tip60/KAT5 KAT10
GCN5/KAT2A MOZ/MYST3/KAT6A TFIIIC90/KAT12
Histone Deacetylases (HDACs) HDAC1 HDAC7 SIRT2
HDAC2 HDAC8 SIRT3
HDAC3 HDAC9 SIRT4
HDAC4 HDAC10 SIRT5
HDAC5 HDAC11 SIRT6
HDAC6 SIRT1 SIRT7
Histone Methyltransferases (HMTs) ASH1 NSD1/KMT3B SETD1A
Clr4/KMT1 PRMT1 SETD8/Pr-SET7/KMT5A
Dot1L/KMT4 PRMT3 SETDB1
EZH2/KMT6 PRMT4/CARM1 SETDB2/KMT1F/CLL8
G9a/EHMT2 PRMT5/JBP1 SMYD2/KMT3C
GLP/EHMT1 PRMT6 SUV39H1
KMT5B/KMT5C Riz1/Riz2/KMT8 SUV39H2
MLL1 NF20 SUV4-20H2/KMT5C
MLL2 RNF40 TRX/ KMT2a
MLL3 SET1A HIF-1/ SET2/HYPB/KMT3A
MLL4 SET1B  
MLL5 SET7/9  
Histone Demethylases (HDMs) ARID1A JHDM1b/FBXL10/KDM2B JMJD2D/KDM4D
ARID5B JHDM2A/KDM3A JMJD3/KDM6B
JARID1A/RBBP2/KDM5A JHDM3A/JMJD2A/KDM4A LSD1/KDM1
JARID1B/PLU1/KDM5B JMJD1A LSD2
JARID1C/SMCX/KDM5C JMJD1B/KDM3B PHF2
JARID1D/SMCY/KDM5D JMJD2A PLU1
JHD1/KDM2 JMJD2B/KDM4B UTX/KDM6A
JHDM1a/FBXL11/KDM2A JMJD2C/GASC1/KDM4C  
DNA Methyltransferases (DNMTs) DNMT1 DNMT3b DNMT1o
DNMT3a DNMT3L  
DNA Demethylases TET1 TET2 TET3