Figure 3
From: Nrf2 null enhances UVB-induced skin inflammation and extracellular matrix damages
MIP-2 and Pro-MMP-9 expression in Nrf2 WT versus Nrf2 KO mice after UVB exposure. Nrf2 WT and KO mice were irradiated with a single dose of UVB (300 mJ/cm2). After 8 h, (A) the MIP-2 expression and (B) the ratios of MIP-2 protein levels in WT and Nrf2 KO mice; (C) the Pro-MMP-9 expression and (D) the ratios of Pro-MMP-9 protein levels in UVB-treated versus control skin (No UVB-treated) were determined; Nrf2 significantly protected against UVB-induced the MIP-2 and pro-MMP-9 expression (p < 0.05). The data are presented as the mean ± SEM.