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Table 4 44 target genes with fold changes<-2 in either FF or FFPE

From: Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA

Gene

Bonferroni P-value (FF sample set)

FDR (Q-value) (FF sample set)

Fold change (FF sample set)

Bonferroni P-value (FFPE sample set)

FDR (Q-value) (FFPE sample set)

Fold change (FFPE sample set)

GLDN

3.17E - 08

4.20E - 10

−5.68982

0.000135

4.60E - 06

−2.52804

CLIC5

1.10E - 06

7.14E - 09

−5.29096

0.000128

4.60E - 06

−3.65321

GBP5

3.95E - 07

3.49E - 09

−4.70136

0.270449

0.002037

−3.34128

CPM

7.00E - 11

8.53E - 12

−4.22426

6.24E - 06

3.19E - 07

−2.34316

ATOH8

7.34E - 09

1.40E - 10

−3.94674

0.057324

0.000599

−3.35103

EXPH5

3.96E - 09

8.90E - 11

−3.62151

0.339217

0.002413

−2.18435

DKK2

1.03E - 09

3.00E - 11

−3.47820

0.135328

0.001155

−2.27702

CUGBP2

1.18E - 07

1.23E - 09

−3.42984

5.43E - 07

4.64E - 08

−2.62785

AQP4

0.000278

8.64E - 07

−3.37647

4.22E - 05

1.80E - 06

−2.62410

COL4A3

2.88E - 06

1.62E - 08

−3.29984

0.003631

6.89E - 05

−2.31972

LATS2

2.90E - 08

4.04E - 10

−3.26820

0.084228

0.000784

−2.67462

CXCL5

0.002516

6.07E - 06

−3.19053

1

0.028874

−1.51815

BNC2

1.13E - 06

7.16E - 09

−2.95318

1.42E - 05

6.62E - 07

−1.97542

CDKN2B

8.98E - 09

1.54E - 10

−2.92826

0.350879

0.002462

−2.06729

HAS3

2.39E - 06

1.37E - 08

−2.89151

1

0.041676

−1.52060

HNMT

8.23E - 10

2.67E - 11

−2.69590

0.000877

1.95E - 05

−1.80218

BACH2

7.75E - 07

5.52E - 09

−2.68793

0.05984

0.000613

−2.47454

NOTCH2

4.20E - 06

2.19E - 08

−2.68482

1

0.011439

−1.98234

PHACTR2

1.09E - 05

4.92E - 08

−2.66216

1

0.011696

−2.13119

AFF3

0.00117

3.08E - 06

−2.64327

0.330617

0.002385

−2.19623

PTPRB

2.98E - 07

2.86E - 09

−2.54037

0.006134

0.000105

−1.76936

IRAK3

3.10E - 06

1.68E - 08

−2.50010

0.06931

0.000683

−1.90606

ARHGAP28

1.24E - 09

3.23E - 11

−2.49453

0.00221

4.53E - 05

−2.07438

ARHGAP29

8.23E - 08

9.24E - 10

−2.46960

0.462337

0.002924

−2.11428

CCDC68

9.93E - 07

6.74E - 09

−2.46136

0.252319

0.00202

−1.79536

CENTD1

4.58E - 05

1.74E - 07

−2.45484

0.000286

7.99E - 06

−2.37418

PDGFRA

8.30E - 07

5.76E - 09

−2.45213

1

0.015458

−1.80164

IGF1

0.000385

1.17E - 06

−2.33199

1

0.017787

−1.55397

MAF

1.47E - 08

2.38E - 10

−2.32004

1

0.022448

−1.74096

CREB5

7.68E - 09

1.40E - 10

−2.29795

0.000166

5.31E - 06

−1.80701

QKI

5.96E - 10

2.32E - 11

−2.26821

0.0408

0.000498

−2.11396

OBFC2A

5.84E - 05

2.10E - 07

−2.22977

0.000653

1.52E - 05

−2.42411

CLEC5A

0.001482

3.73E - 06

−2.21928

0.072505

0.000688

−1.75105

COL4A4

0.001462

3.73E - 06

−2.18249

1

0.017007

−1.94555

PRTG

0.00085

2.30E - 06

−2.16704

0.000415

1.06E - 05

−3.39011

CTSS

7.00E - 07

5.24E - 09

−2.11030

1

0.045919

−1.46121

OSBPL3

4.65E - 06

2.38E - 08

−2.10227

0.05406

0.000583

−1.67649

BCL11B

0.01734

3.27E - 05

−2.09141

0.071549

0.000688

−2.19192

PRRG1

6.71E - 07

5.16E - 09

−2.08980

1

0.025403

−1.67003

ANTXR2

1.94E - 05

8.44E - 08

−2.06102

0.36279

0.002497

−1.90464

PGR

0.003108

7.26E - 06

−2.03599

0.480485

0.002965

−1.87897

BAALC

0.005685

1.24E - 05

−2.01197

0.009384

0.000146

−1.83602

LIMD1

4.71E - 05

1.76E - 07

−1.87690

0.617357

0.003677

−2.02599

NFIB

2.16E - 06

1.28E - 08

−1.49800

1

0.015881

−2.01869

  1. Note: If fold changes in the FF or FFPE sample sets are <-2, they are denoted in italics, respectively. If the Bonferroni P-value or FDR (Q-value) are <0.05 or <0.01, they are labeled in bold font, respectively.
  2. FF=Fresh Frozen tissues.
  3. FFPE=Formalin-Fixed Paraffin-Embedded tissues.
  4. FDR=False Discovery Rate.
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Cell & Bioscience

ISSN: 2045-3701

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