MiR-206 inhibits liver metastasis of GC in vivo. (A) Representative macroscopic pictures of mouse liver, 42 Days after inoculation, (The upper). Representative photographs of H&E stained spontaneous liver metastases. Magnification:10× (The lower). The results show that tumor nodules in P2GM-miR-206 group were smaller and fewer as compared to the control group. (B) Numbers of liver metastatic loci were counted and compared between mice bearing SGC-7901 vector control cells and SGC-7901 cells expressing miR-206. Data represent the means ± SEM, (***P < 0.0001). (C) Relative mRNA level of putative targets of miR-206 between SGC-7901-miR-P2GM and SGC-7901-miR-206 cells. (D) The relative mRNA level of putative targets of miR-206 between GES-1 and SGC-7901 cell lines.