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Figure 2 | Cell & Bioscience

Figure 2

From: MicroRNA-206 suppresses gastric cancer cell growth and metastasis

Figure 2

Forced expression of miR-206 suppresses the proliferation of SGC-7901 gastric cancer cells. (A) Total levels of miR-206 in SGC-7901 cells transfected with the miR-ctrl or the synthetic mimics of miR-206, 206mi (***P < 0.0001). (B) MTT assays for SGC-7901 cells transfected with miR-206 mimics at a final concentration of 100 nM. Starting from 24 h post-transfection, the assays was read every 24 h for 5 consecutive days. Results are expressed as means ± SEM from three independent experiments. (***P < 0.0001). (C) A histogram depicting cell cycle distribution of SGC-7901 cells transiently transfected with P2GM-miR-206 or P2GM-ctrl (100 nM). The results represent the means ± SEM of three independent experiments (*P < 0.05). (D) Cells staining positive for Annexin V-FITC and negative for PI at 48 h post-transfection were considered to have undergone apoptosis. (E) Average apoptotic rate of three independent experiments ± SEM are shown (***P < 0.0001).

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