Table 3 Univariate and multivariate analysis of association of clinicopathologic features with 5-year survival in colon cancer cases
Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
Relative risk | 95% CI | P Value | Relative risk | 95% CI | P Value | |
Age at diagnosis | 1.091 | 1.063, 1.119 | <0.001 | 1.114 | 1.083, 1.145 | <0.001 |
Gender | ||||||
Male | 1.000(Ref.) | - | - | |||
Female | 0.729 | 0.438, 1.212 | 0.223 | |||
Tumor anatomical location | ||||||
Right hemicolon cancer | 1.000(Ref.) | - | - | |||
Left hemicolon cancer | 1.000 | 0.610,1.640 | 0.999 | |||
T stage | ||||||
T1 | 0.000 | 0.000, >105 | 0.973 | |||
T2 | 0.951 | 0.395, 2.290 | 0.910 | |||
T3 | 1.152 | 0.685, 1.937 | 0.595 | |||
T4 | 1.000(Ref.) | - | - | |||
N stage | ||||||
N0 | 1.000(Ref.) | - | - | |||
N1 | 1.308 | 0.760, 2.252 | 0.332 | |||
N2 | 1.356 | 0.646, 2.843 | 0.421 | |||
M stage | ||||||
M0 | 1.000(Ref.) | - | - | |||
M1 | 1.308 | 0.697, 2.454 | 0.403 | |||
TNM stage | ||||||
I | 1.000(Ref.) | - | - | |||
II | 0.634 | 0.242, 1.664 | 0.355 | |||
III | 0.998 | 0.378, 2.638 | 0.997 | |||
IV | 1.029 | 0.362, 2.922 | 0.957 | |||
Pathology Grade | ||||||
Well | 1.000(Ref.) | - | - | 1.000(Ref.) | - | - |
Moderate | 1.666 | 0.912, 3.046 | 0.097 | 1.348 | 0.721, 2.519 | 0.349 |
Poor/undifferentiated | 1.845 | 0.950, 3.583 | 0.070 | 2.915 | 1.453, 5.848 | 0.003 |
eIF4E | ||||||
Low expression | 1.000(Ref.) | - | - | 1.000(Ref.) | - | - |
High expression | 1.885 | 1.128, 3.150 | 0.016 | 2.417 | 1.413, 4.134 | 0.001 |
αvβ6 | ||||||
Negative | 1.000(Ref.) | - | - | 1.000(Ref.) | - | - |
Positive | 1.741 | 1.061, 2.857 | 0.028 | 2.393 | 1.421, 4.028 | 0.001 |