Protein expression of eIF4E and integrin αvβ6 in colon cancer can predict clinical significance, reveal their correlation and imply possible mechanism of interaction

Table 1 Association between eIF4E expression, integrin αvβ6 expression and clinicopathologic variables in colon cancer cases

Clinicopathological factors	n	eIF4E expression		Value	Integrin αvβ6 expression		P Value
		High (n = 74)	Low (n = 64)		Positive (n = 54)	Negative (n = 84)
Gender				0.345			0.927
Male	76	38	38		30	46
Female	62	36	26		24	38
Age(years)				0.874			0.108
<60	70	38	32		32	38
≥60	68	36	32		22	46
Tumor anatomical location				0.634			0.773
Right hemicolon cancer	72	32	40		43	29
Left hemicolon cancer	66	32	34		41	25
T stage				0.072			0.011
T1^#	1	0	1		0	1
T2^#	13	8	5		2	11
T3	55	23	32		17	38
T4	69	43	26		35	34
N stage				0.067			0.109
N0	76	34	42		26	50
N1	44	28	16		17	27
N2	18	12	6		11	7
M stage
M0	114	57	57	0.063	40	74	0.034
M1	24	17	7		14	10
TNM stage				0.009			0.012
I - II	72	31	41		21	51
III-IV	66	43	23		33	33
Differentiation				0.959			0.209
Well	50	26	24		15	35
Moderate	55	30	25		23	32
Poor/undifferentiated	33	18	15		16	17
Survival (60-month follow-up)				0.013*			0.025*
Death	63	40	23		30	33
Censored	75	34	41		24	51

ISSN: 2045-3701