Figure 7From: Deficiency in steroid receptor coactivator 3 enhances cytokine production in IgE-stimulated mast cells and passive systemic anaphylaxis in miceSRC-3 deficiency leads to increased MAPK pathway activation. BMMCs were stimulated with anti-DNP IgE 1 μg/ml for 4 h, and then treated with DNP-HSA 10 ng/ml for various times. Whole cell lysates were analyzed by western-blotting for ERK, p-ERK, JNK, p-JNK, p38 and p-p38. Representative images are shown from three independent experiments.Back to article page