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Figure 3 | Cell & Bioscience

Figure 3

From: Control of spontaneous ovarian tumors by CD8+ T cells through NKG2D-targeted delivery of antigenic peptide

Figure 3

Major histocompatibility complex class I presentation of ovalbumin (OVA) peptide to OVA-specific CD8 + T cells by MOVCAR cells treated with NKG2D-Fc-RO. (A) Flow cytometry characterization of OVA-specific CD8+ T-cell activation by MOVCAR cells treated with different chimeric proteins followed by incubation with 2 × 105 OVA-specific cytotoxic CD8+ T lymphocytes (CTLs). OVA-specific CD8+ T-cell activation was determined by CD8 and IFN-γ staining. (B) Representative bar graph depicting the % of IFN-γ-secreting OVA-specific CD8+ T cells out of total OVA-specific T cells (mean ± SD).

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