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Table 3 Association of SNX24 genetic variants with CAA formation risk in Taiwanese Kawasaki disease by logistic regression analysis

From: Sorting nexin 24 genetic variation associates with coronary artery aneurysm severity in Kawasaki disease patients

SNX24 genetic variants

Odds ratio

95% CI

p value

Adjusted by fever duration (days)

   

  rs154507

1.90

0.88-2.83

0.046

  rs27740

1.90

0.88-2.83

0.046

  rs26371

0.60

0.32-1.04

0.105

  rs6595415

1.74

0.84-2.64

0.077

  rs17149732

1.74

0.84-2.64

0.077

  rs17149748

1.83

0.86-2.72

0.057

  rs1038078

1.71

0.82-2.58

0.087

  rs28891

0.41

0.25-0.75

0.003

  rs6595423

1.74

0.84-2.64

0.077

Adjusted by 1st IVIG used (days after the first date with fever)

   

  rs154507

1.61

0.88-2.83

0.114

  rs27740

1.61

0.88-2.83

0.114

  rs26371

0.57

0.32-1.04

0.059

  rs6595415

1.52

0.84-2.64

0.152

  rs17149732

1.52

0.84-2.64

0.152

  rs17149748

1.57

0.86-2.72

0.127

  rs1038078

1.50

0.82-2.58

0.171

  rs28891

0.42

0.25-0.75

0.002

  rs6595423

1.52

0.84-2.64

0.152

  1. SNX24, sorting nexin 24; IVIG, Intravenous immunoglobulin; CAA, Coronary artery aneurysm; CI, confidence interval.
  2. A logistic regression model was performed by using the indicated predictors including fever duration (days) or 1st IVIG used time (days after the first date with fever).
  3. Bold, emphasizing statistical significance was considered as p value <0.006 (0.05/9).