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Table 2 Summary of the SNPs associated with the CAA formation in Taiwanese Kawasaki disease

From: Sorting nexin 24 genetic variation associates with coronary artery aneurysm severity in Kawasaki disease patients

SNP Chromosome Cytoband Physical position Nearest genes   CAA- CAA+   
       No. (%) No. (%) p value Odds ratio (95% CI)
rs154507 5 q23.2 122228806 SNX24 GG 24 (12.9) 14 (18.4) 0.234 1.94 (0.86–4.41)
      GC 92 (49.5) 41 (54.0)   1.49 (0.81–2.74)
      CC 70 (37.6) 21 (27.6)   1
rs27740 5 q23.2 122232671 SNX24 TT 24 (12.9) 14 (18.4) 0.234 1.94 (0.86–4.41)
      TA 92 (49.5) 41 (54.0)   1.49 (0.81–2.74)
      AA 70 (37.6) 21 (27.6)   1
rs26371 5 q23.2 122234424 SNX24 TT 44 (23.7) 12 (15.8) 0.123 0.45 (0.20–1.01)
      TC 99 (53.2) 38 (50.0)   0.63 (0.34–1.17)
      CC 43 (23.1) 26 (34.2)   1
rs6595415 5 q23.2 122234657 SNX24 TT 23 (12.4) 15 (19.7) 0.198 2.07 (0.93–4.61)
      TC 90 (48.4) 38 (50.0)   1.34 (0.73–2.45)
      CC 73 (39.2) 23 (30.3)   1
rs17149732 5 q23.2 122249811 SNX24 TT 23 (12.4) 14 (18.4) 0.261 1.93 (0.86–4.36)
      TG 90 (48.4) 39 (51.3)   1.38 (0.75–2.51)
      GG 73 (39.2) 23 (30.3)   1
rs17149748 5 q23.2 122295266 SNX24 CC 23 (12.4) 14 (18.4) 0.242 1.96 (0.87–4.45)
      CT 91 (49.2) 40 (52.6)   1.42 (0.77–2.60)
      TT 71 (38.4) 22 (29.0)   1
rs1038078 5 q23.2 122309550 SNX24 AA 23 (12.4) 14 (18.4) 0.283 1.91 (0.84–4.30)
      AG 91 (48.9) 39 (51.3)   1.34 (0.74–2.45)
      GG 72 (38.7) 23 (30.3)   1
rs28891 5 q23.2 122311523 SNX24 CC 39 (21.0) 8 (10.6) 0.006 0.29 (0.12–0.70)
      CT 99 (53.2) 34 (44.7)   0.48 (0.27–0.87)
      TT 48 (25.8) 34 (44.7)   1
rs6595423 5 q23.2 122341433 SNX24 CC 23 (12.4) 13 (17.1) 0.322 1.79 (0.79–4.10)
      CT 90 (48.4) 40 (52.6)   1.41 (0.78–2.57)
      TT 73 (39.2) 23 (30.3)   1
  1. SNX24, sorting nexin 24; SNP, single nucleotide polymorphism; CAA, Coronary artery aneurysm; CI, confidence interval.
  2. p-values were obtained by chi-square test.
  3. Bold, emphasizing statistical significance was considered as p value <0.05.