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Table 1 Genotype distributions of SNX24 gene SNPs in Taiwanese KD patients and controls

From: Sorting nexin 24 genetic variation associates with coronary artery aneurysm severity in Kawasaki disease patients

SNP

Chromosome

Cytoband

Physical position

Nearest genes

 

Controls

KD patients

      

No. (%)

No. (%)

p value

Odds ratio (95% CI)

rs154507

5

q23.2

122228806

SNX24

GG

146 (13.2)

38 (14.5)

0.755

1.17 (0.76–1.78)

     

GC

553 (50.0)

133 (50.8)

 

1.08 (0.80–1.45)

     

CC

408 (36.8)

91 (34.7)

 

1

rs27740

5

q23.2

122232671

SNX24

TT

156 (14.1)

38 (14.5)

0.867

1.08 (0.71–1.65)

     

TA

547 (49.4)

133 (50.8)

 

1.08 (0.80–1.45)

     

AA

404 (36.5)

91 (34.7)

 

1

rs26371

5

q23.2

122234424

SNX24

TT

217 (19.6)

56 (21.4)

0.690

1.19 (0.80–1.76)

     

TC

573 (51.8)

137 (52.3)

 

1.10 (0.80–1.51)

     

CC

317 (28.7)

69 (26.3)

 

1

rs6595415

5

q23.2

122234657

SNX24

TT

151 (13.6)

38 (14.5)

0.842

1.12 (0.73–1.70)

     

TC

530 (47.9)

128 (48.9)

 

1.07 (0.80–1.44)

     

CC

426 (38.5)

96 (36.6)

 

1

rs17149732

5

q23.2

122249811

SNX24

TT

146 (13.2)

37 (14.1)

0.784

1.14 (0.74–1.73)

     

TG

530 (47.9)

129 (49.2)

 

1.09 (0.81–1.46)

     

GG

430 (38.9)

96 (36.6)

 

1

rs17149748

5

q23.2

122295266

SNX24

CC

150 (13.6)

37 (14.1)

0.710

1.13 (0.74–1.72)

     

CT

532 (48.1)

131 (50.0)

 

1.13 (0.84–1.51)

     

TT

425 (38.4)

93 (35.5)

 

1

rs1038078

5

q23.2

122309550

SNX24

AA

147 (13.3)

37 (14.1)

0.676

1.15 (0.75–1.76)

     

AG

526 (47.5)

130 (49.6)

 

1.13 (0.84–1.51)

     

GG

434 (39.2)

95 (36.3)

 

1

rs28891

5

q23.2

122311523

SNX24

CC

187 (16.9)

47 (17.9)

0.836

1.12 (0.75–1.67)

     

CT

554 (50.1)

133 (50.8)

 

1.07 (0.79–1.45)

     

TT

366 (33.1)

82 (31.3)

 

1

rs6595423

5

q23.2

122341433

SNX24

CC

144 (13.0)

36 (13.7)

0.667

1.14 (0.75–1.75)

     

CT

524 (47.3)

130 (49.6)

 

1.13 (0.85–1.52)

     

TT

439 (39.7)

96 (36.6)

 

1

  1. SNX24, sorting nexin 24; SNP, single nucleotide polymorphism; CI, confidence interval.
  2. p-values were obtained by chi-square test.
  3. Bold, emphasizing statistical significance was considered as p value <0.006 (0.05/9).