|
SNP
|
Chromosome
|
Cytoband
|
Physical position
|
Nearest genes
| |
Controls
|
KD patients
|
|---|
| | | | | | |
No. (%)
|
No. (%)
|
p value
|
Odds ratio (95% CI)
|
|---|
|
rs154507
|
5
|
q23.2
|
122228806
|
SNX24
|
GG
|
146 (13.2)
|
38 (14.5)
|
0.755
|
1.17 (0.76–1.78)
|
| | | | | |
GC
|
553 (50.0)
|
133 (50.8)
| |
1.08 (0.80–1.45)
|
| | | | | |
CC
|
408 (36.8)
|
91 (34.7)
| |
1
|
|
rs27740
|
5
|
q23.2
|
122232671
|
SNX24
|
TT
|
156 (14.1)
|
38 (14.5)
|
0.867
|
1.08 (0.71–1.65)
|
| | | | | |
TA
|
547 (49.4)
|
133 (50.8)
| |
1.08 (0.80–1.45)
|
| | | | | |
AA
|
404 (36.5)
|
91 (34.7)
| |
1
|
|
rs26371
|
5
|
q23.2
|
122234424
|
SNX24
|
TT
|
217 (19.6)
|
56 (21.4)
|
0.690
|
1.19 (0.80–1.76)
|
| | | | | |
TC
|
573 (51.8)
|
137 (52.3)
| |
1.10 (0.80–1.51)
|
| | | | | |
CC
|
317 (28.7)
|
69 (26.3)
| |
1
|
|
rs6595415
|
5
|
q23.2
|
122234657
|
SNX24
|
TT
|
151 (13.6)
|
38 (14.5)
|
0.842
|
1.12 (0.73–1.70)
|
| | | | | |
TC
|
530 (47.9)
|
128 (48.9)
| |
1.07 (0.80–1.44)
|
| | | | | |
CC
|
426 (38.5)
|
96 (36.6)
| |
1
|
|
rs17149732
|
5
|
q23.2
|
122249811
|
SNX24
|
TT
|
146 (13.2)
|
37 (14.1)
|
0.784
|
1.14 (0.74–1.73)
|
| | | | | |
TG
|
530 (47.9)
|
129 (49.2)
| |
1.09 (0.81–1.46)
|
| | | | | |
GG
|
430 (38.9)
|
96 (36.6)
| |
1
|
|
rs17149748
|
5
|
q23.2
|
122295266
|
SNX24
|
CC
|
150 (13.6)
|
37 (14.1)
|
0.710
|
1.13 (0.74–1.72)
|
| | | | | |
CT
|
532 (48.1)
|
131 (50.0)
| |
1.13 (0.84–1.51)
|
| | | | | |
TT
|
425 (38.4)
|
93 (35.5)
| |
1
|
|
rs1038078
|
5
|
q23.2
|
122309550
|
SNX24
|
AA
|
147 (13.3)
|
37 (14.1)
|
0.676
|
1.15 (0.75–1.76)
|
| | | | | |
AG
|
526 (47.5)
|
130 (49.6)
| |
1.13 (0.84–1.51)
|
| | | | | |
GG
|
434 (39.2)
|
95 (36.3)
| |
1
|
|
rs28891
|
5
|
q23.2
|
122311523
|
SNX24
|
CC
|
187 (16.9)
|
47 (17.9)
|
0.836
|
1.12 (0.75–1.67)
|
| | | | | |
CT
|
554 (50.1)
|
133 (50.8)
| |
1.07 (0.79–1.45)
|
| | | | | |
TT
|
366 (33.1)
|
82 (31.3)
| |
1
|
|
rs6595423
|
5
|
q23.2
|
122341433
|
SNX24
|
CC
|
144 (13.0)
|
36 (13.7)
|
0.667
|
1.14 (0.75–1.75)
|
| | | | | |
CT
|
524 (47.3)
|
130 (49.6)
| |
1.13 (0.85–1.52)
|
| | | | | |
TT
|
439 (39.7)
|
96 (36.6)
| |
1
|
- SNX24, sorting nexin 24; SNP, single nucleotide polymorphism; CI, confidence interval.
- p-values were obtained by chi-square test.
- Bold, emphasizing statistical significance was considered as p value <0.006 (0.05/9).
