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Table 1 Genotype distributions of SNX24 gene SNPs in Taiwanese KD patients and controls
| SNP | Chromosome | Cytoband | Physical position | Nearest genes | Controls | KD patients | |||
|---|---|---|---|---|---|---|---|---|---|
| No. (%) | No. (%) | p value | Odds ratio (95% CI) | ||||||
| rs154507 | 5 | q23.2 | 122228806 | SNX24 | GG | 146 (13.2) | 38 (14.5) | 0.755 | 1.17 (0.76–1.78) |
| GC | 553 (50.0) | 133 (50.8) | 1.08 (0.80–1.45) | ||||||
| CC | 408 (36.8) | 91 (34.7) | 1 | ||||||
| rs27740 | 5 | q23.2 | 122232671 | SNX24 | TT | 156 (14.1) | 38 (14.5) | 0.867 | 1.08 (0.71–1.65) |
| TA | 547 (49.4) | 133 (50.8) | 1.08 (0.80–1.45) | ||||||
| AA | 404 (36.5) | 91 (34.7) | 1 | ||||||
| rs26371 | 5 | q23.2 | 122234424 | SNX24 | TT | 217 (19.6) | 56 (21.4) | 0.690 | 1.19 (0.80–1.76) |
| TC | 573 (51.8) | 137 (52.3) | 1.10 (0.80–1.51) | ||||||
| CC | 317 (28.7) | 69 (26.3) | 1 | ||||||
| rs6595415 | 5 | q23.2 | 122234657 | SNX24 | TT | 151 (13.6) | 38 (14.5) | 0.842 | 1.12 (0.73–1.70) |
| TC | 530 (47.9) | 128 (48.9) | 1.07 (0.80–1.44) | ||||||
| CC | 426 (38.5) | 96 (36.6) | 1 | ||||||
| rs17149732 | 5 | q23.2 | 122249811 | SNX24 | TT | 146 (13.2) | 37 (14.1) | 0.784 | 1.14 (0.74–1.73) |
| TG | 530 (47.9) | 129 (49.2) | 1.09 (0.81–1.46) | ||||||
| GG | 430 (38.9) | 96 (36.6) | 1 | ||||||
| rs17149748 | 5 | q23.2 | 122295266 | SNX24 | CC | 150 (13.6) | 37 (14.1) | 0.710 | 1.13 (0.74–1.72) |
| CT | 532 (48.1) | 131 (50.0) | 1.13 (0.84–1.51) | ||||||
| TT | 425 (38.4) | 93 (35.5) | 1 | ||||||
| rs1038078 | 5 | q23.2 | 122309550 | SNX24 | AA | 147 (13.3) | 37 (14.1) | 0.676 | 1.15 (0.75–1.76) |
| AG | 526 (47.5) | 130 (49.6) | 1.13 (0.84–1.51) | ||||||
| GG | 434 (39.2) | 95 (36.3) | 1 | ||||||
| rs28891 | 5 | q23.2 | 122311523 | SNX24 | CC | 187 (16.9) | 47 (17.9) | 0.836 | 1.12 (0.75–1.67) |
| CT | 554 (50.1) | 133 (50.8) | 1.07 (0.79–1.45) | ||||||
| TT | 366 (33.1) | 82 (31.3) | 1 | ||||||
| rs6595423 | 5 | q23.2 | 122341433 | SNX24 | CC | 144 (13.0) | 36 (13.7) | 0.667 | 1.14 (0.75–1.75) |
| CT | 524 (47.3) | 130 (49.6) | 1.13 (0.85–1.52) | ||||||
| TT | 439 (39.7) | 96 (36.6) | 1 | ||||||
