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Table 1 Summary of epigenetic factors that regulate CSCs

From: Epigenetic regulation in adult stem cells and cancers

Name of gene Protein function Cancer type
TET family (TET1, TET2, TET3) DNA demethylases Prostate cancer, breast cancer, liver cancer, lung cancer, leukemia, melanoma
Dnmt1 DNA methylase Leukemia
Ezh2 H3K27me3 HMT Leukemia, breast cancer, prostate cancer, pancreatic cancer, ovarian cancer
Bmi1 PRC1 component Glioblastoma
MLL1 H3K4me3 HMT Glioblastoma
Lsd1 H3K4/K9 demethylase Teratocarcinoma, embryonic carcinoma, seminoma