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Table 1 Subunit composition of H3K4 methyltransferase complexes in yeast andhuman

From: Histone H3 lysine 4 methyltransferases and demethylases in self-renewal anddifferentiation of stem cells

Yeast SET1

Human SET1A

Human SET1B

Human MLL1

Human MLL2

Human MLL3

Human MLL4

Human MLL5*

SET1

SET1A

SET1B

MLL1

MLL2

MLL3

MLL4

Mll5

Cps60/Bre2

ASH2L

ASH2L

ASH2L

ASH2L

ASH2L

ASH2L

HCF1

Cps50/Swd1

RBBP5

RBBP5

RBBP5

RBBP5

RBBP5

RBBP5

OGT

Cps30/Swd3

WDR5

WDR5

WDR5

WDR5

WDR5

WDR5

STK38

Cpd25/Sdc1

DPY-30

DPY-30

DPY-30

DPY-30

DPY-30

DPY-30

PPP1CA

Cps40/Spp1

CFP1

CFP1

    

PPP1CB

Cps35/Swd2

WDR82

WDR82

    

PPP1CC

Cps15/Shg1

 

BOD1/BOD1L

    

ACTB

 

HCF1/2

HCF1/2

HCF1/2

HCF1/2

NCOA6

NCOA6

 
   

MENIN

MENIN

UTX

UTX

 
    

PSIP1

PTIP

PTIP

 
     

PA1

PA1

 
  1. * The subunits of MLL5 are not related to those of SET1, SET1A/B, andMLL1−4.