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Table 1 Subunit composition of H3K4 methyltransferase complexes in yeast andhuman

From: Histone H3 lysine 4 methyltransferases and demethylases in self-renewal anddifferentiation of stem cells

Yeast SET1 Human SET1A Human SET1B Human MLL1 Human MLL2 Human MLL3 Human MLL4 Human MLL5*
SET1 SET1A SET1B MLL1 MLL2 MLL3 MLL4 Mll5
Cps60/Bre2 ASH2L ASH2L ASH2L ASH2L ASH2L ASH2L HCF1
Cps50/Swd1 RBBP5 RBBP5 RBBP5 RBBP5 RBBP5 RBBP5 OGT
Cps30/Swd3 WDR5 WDR5 WDR5 WDR5 WDR5 WDR5 STK38
Cpd25/Sdc1 DPY-30 DPY-30 DPY-30 DPY-30 DPY-30 DPY-30 PPP1CA
Cps40/Spp1 CFP1 CFP1      PPP1CB
Cps35/Swd2 WDR82 WDR82      PPP1CC
Cps15/Shg1   BOD1/BOD1L      ACTB
  HCF1/2 HCF1/2 HCF1/2 HCF1/2 NCOA6 NCOA6  
    MENIN MENIN UTX UTX  
     PSIP1 PTIP PTIP  
      PA1 PA1  
  1. * The subunits of MLL5 are not related to those of SET1, SET1A/B, andMLL1−4.