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Table 1 Subunit composition of H3K4 methyltransferase complexes in yeast andhuman
| Yeast SET1 | Human SET1A | Human SET1B | Human MLL1 | Human MLL2 | Human MLL3 | Human MLL4 | Human MLL5* |
|---|---|---|---|---|---|---|---|
| SET1 | SET1A | SET1B | MLL1 | MLL2 | MLL3 | MLL4 | Mll5 |
| Cps60/Bre2 | ASH2L | ASH2L | ASH2L | ASH2L | ASH2L | ASH2L | HCF1 |
| Cps50/Swd1 | RBBP5 | RBBP5 | RBBP5 | RBBP5 | RBBP5 | RBBP5 | OGT |
| Cps30/Swd3 | WDR5 | WDR5 | WDR5 | WDR5 | WDR5 | WDR5 | STK38 |
| Cpd25/Sdc1 | DPY-30 | DPY-30 | DPY-30 | DPY-30 | DPY-30 | DPY-30 | PPP1CA |
| Cps40/Spp1 | CFP1 | CFP1 | PPP1CB | ||||
| Cps35/Swd2 | WDR82 | WDR82 | PPP1CC | ||||
| Cps15/Shg1 | BOD1/BOD1L | ACTB | |||||
| HCF1/2 | HCF1/2 | HCF1/2 | HCF1/2 | NCOA6 | NCOA6 | ||
| MENIN | MENIN | UTX | UTX | ||||
| PSIP1 | PTIP | PTIP | |||||
| PA1 | PA1 |
