Figure 6

17-DMAG increased survivin protein in bone marrow cells after irradiation. Bone marrow cells were collected from femur bones and analyzed using Western blot for its survivin expression 30 days after irradiation at 8.75 Gy. (A) A representative Western blot of survivin. (B) Densitometric quantitation of survivin protein.* p < 0.01 vs. Veh/sham, 17-D/sham, and 17D/RI groups; ** p < 0.001 vs. Veh/RI groups. Error bars indicate the SEM for at least four independent experiments. Veh: vehicle; 17-D: 17-DMAG; RI: radiation injury.