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Figure 2 | Cell & Bioscience

Figure 2

From: Integration of mechanical and chemical signals by YAP and TAZ transcription coactivators

Figure 2

Phenotypes of intestinal crypt cells in animal models concerning the cross-talk between the Hippo and Wnt pathways. The protein level and subcellular localization of YAP in crypt cells of each mouse model are illustrated. The amount of transcriptionally active β-catenin in cell nucleus is also shown. However, for simplicity, the mechanisms are not reflected and the amount of transcriptionally active β-catenin does not suggest the change of total β-catenin protein level or subcellular localization.

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