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Table 3 Effect of SVPII on M-NFS-60 cell cycle progression (96 h; % of total cells)

From: Scorpion venom peptide SPVII promotes irradiated cells proliferation and increases the expression of the IL-3 receptor

Group G0-G1 G2-M S
96 h Control 45.51 ± 13.52 8.51 ± 2.95 41.97 ± 16.47
Serum-free control 71.56 ± 5.60 8.16 ± 5.10 20.29 ± 10.71
SVPII 3 mg/L 41.22 ± 14.96 * 4.29 ± 2.70 54.47 ± 17.66 *
IL-3 10 μg/L 51.81 ± 18.23 3.11 ± 1.40 44.88 ± 19.87
  1. Cells were incubated in media containing 10% FCS + 62 μg/L rhM-CSF for 96 h (96 h control). All other cultures were treated with media plus rhM-CSF but without serum for 24 h and then treated for an additional 72 h with media supplemented with 10% FCS + 62 μg/L rhM-CSF (serum-free control) or treated with SVPII 3 mg/L or IL-3 10 μg/L in the same media. * P < 0.05 vs. serum-free control.