Scorpion venom peptide SPVII promotes irradiated cells proliferation and increases the expression of the IL-3 receptor

Cell & Bioscience

Table 3 Effect of SVPII on M-NFS-60 cell cycle progression (96 h; % of total cells)

Group	G0-G1	G2-M	S
96 h Control	45.51 ± 13.52	8.51 ± 2.95	41.97 ± 16.47
Serum-free control	71.56 ± 5.60	8.16 ± 5.10	20.29 ± 10.71
SVPII 3 mg/L	41.22 ± 14.96 *	4.29 ± 2.70	54.47 ± 17.66 *
IL-3 10 μg/L	51.81 ± 18.23	3.11 ± 1.40	44.88 ± 19.87

Cells were incubated in media containing 10% FCS + 62 μg/L rhM-CSF for 96 h (96 h control). All other cultures were treated with media plus rhM-CSF but without serum for 24 h and then treated for an additional 72 h with media supplemented with 10% FCS + 62 μg/L rhM-CSF (serum-free control) or treated with SVPII 3 mg/L or IL-3 10 μg/L in the same media. * P < 0.05 vs. serum-free control.