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Table 2 Effect of SVPII on M-NFS-60 cell cycle progression (24 h; % of total cells)

From: Scorpion venom peptide SPVII promotes irradiated cells proliferation and increases the expression of the IL-3 receptor

Group

G0-G1

G2-M

S

24 h Control

40.02 ± 5.25*

2.68 ± 4.58

56.76 ± 1.09*

Serum-free control

57.17 ± 1.66

2.67 ± 3.73

39.88 ± 1.95

SVPII 3 mg/L

39.92 ± 2.15*

2.17 ± 3.45

57.98 ± 5.68*

IL-3 10 μg/L

45.41 ± 3.63*

1.14 ± 1.67

53.13 ± 5.01*

  1. The 24 h control cells were incubated in media containing 10% FCS + 62 μg/L rhM-CSF. All other cultures were treated with media plus rhM-CSF but without serum (serum-free media) or incubated in this same media supplemented with SVPII or IL-3 for 24 h. * P < 0.05 vs. serum-free control.