Figure 2
From: Specific structure and unique function define the hemicentin

Similarity analysis on hemicentin family members shows highly conserved amino acid regions between the amino acid terminal vWA domain and the first Ig module. Comparative alignment between C. elegans (Ce) hemicentin, and hemicentin 1/hemicentin 2 exhibits four specific sequence motifs shared by corresponding genes in human (Hs), mouse (Mm), and Xenopus (Xt). These conserved sequences distinguish hemicentin family members across multiple species.