From: Overexpression of MACC1 and Its significance in human Breast Cancer Progression
 | Univariate analysis | Multivariate | ||
---|---|---|---|---|
 | P | Hazard ratio (95% CI) | P | Hazard ratio (95% CI) |
Age | Â | Â | Â | Â |
 ≤45 | 0.808 | 1.061 (0.657-1.713) |  |  |
 >45 |  |  |  |  |
Tumor size (cm) | Â | Â | Â | Â |
 ≤2 | <0.001 | 3.449 (2.131-5.584) | <0.001 | 2.834(1.741-4.612) |
 >2 | ||||
Lymph node status | Â | Â | Â | Â |
 Negative | <0.001 | 3.657 (1.960-6.823) | 0.001 | 2.936(1.540-5.597) |
 Positive | ||||
ER | Â | Â | Â | Â |
 Positive | 0.793 | 0.938 (0.583-1.509) |  |  |
 Negative | ||||
PR | Â | Â | Â | Â |
 Positive | 0.036 | 0.603 (0.375-0.968) | 0.002 | 0.465 (0.286-0.757) |
 Negative | ||||
ErbB-2 | Â | Â | Â | Â |
 Positive | 0.886 | 0.937 (0.383-2.292) |  |  |
 Negative | ||||
MACC1 expression | Â | Â | Â | Â |
 Positive | <0.001 | 4.564 (2.392-8.709) | 0.001 | 3.190 (1.651-6.163) |
 Negative |