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Table 2 Correlation between MACC1 expression and the clinicopathologic characteristics of the breast cancer patients

From: Overexpression of MACC1 and Its significance in human Breast Cancer Progression

Characteristics Cohort 1 Cohort 2
  MACC1 expression MACC1 expression
  Low High P-value Low High P-value
Age       
 ≤45 44 51 0.647 29 49 0.504
 >45 65 85   45 62  
Menopausal status       
 Premenopausal 56 60 0.799    
 Postmenopausal 51 51     
Clinical stage       
 I 43 38 0.001 19 2 <0.001
 II 45 46   37 43  
 III 15 25   14 45  
 IV 5 28   4 21  
T classification       
 T1 61 49 0.019 23 13 <0.001
 T2 39 68   39 53  
 T3 6 12   11 30  
 T4 3 7   1 15  
N classification       
 N0 67 68 0.050 44 26 <0.001
 N1 25 26   24 54  
 N2 12 29   4 26  
 N3 5 13   2 5  
Distant metastasis       
 Yes 104 108 <0.001 0 8 0.022
 No 5 28   74 103  
Estrogen receptor       
 Positive 79 95 0.653 36 65 0.185
 Negative 30 41   38 46  
Progesterone receptor       
 Positive 63 83 0.990 43 67 0.760
 Negative 32 42   31 44  
Her2       
 Positive 21 22 0.862 8 13 0.480
 Negative 71 79   36 41  
Endocrine therapy       
 tamoxifen 62 60 0.614    
 No treatment 45 50