Figure 2From: Regulation of germ layer formation by pluripotency factors during embryogenesisCorrelation between pluripotency factors and differentiation signals during Xenopus germ layer formation. Germ layers are formed in strict spatiotemporal patterns. Either POU-V factors or germ layer inducing signals have specific localizations and exhibit different levels of activities during the process of germ layer formation of Xenopus embryos. POU-V factors antagonize the differentiation signals, so as to ensure that germ layer formation can occur in the correct spatiotemporal patterns (See text for details). An: animal pole; Vg: vegetal pole; D: dorsal side; V: ventral side. Reproduced from [42] with modifications.Back to article page