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Figure 3 | Cell & Bioscience

Figure 3

From: Regulation of TGF-β receptor activity

Figure 3

Various mechanisms regulate TGF-β receptor activity. (A) Regulation of TGF-β receptor activity by multiple receptor-binding proteins. BAMBI and ETV6-NTRK3 attenuates TGF-β receptor activity by interfering receptor heterocomplex formation, while FKBP12 blocks GS domain phosphorylation of TβRI by TβRII at the basal state. (B) Sumoylation promotes TβRI activity.

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