Table 1 Components of the Smc complexes and regulatory proteins in different organisms
| Â | S. cerevisiae | S. pombe | H. sapiens |
|---|---|---|---|
Cohesin | Smc1 | Psm1 | Smc1 |
| Â | Smc3 | Psm3 | Smc3 |
| Â | Mcd1/Scc1 | Rad21 | Scc1/Rad21 |
| Â | IRR1/Scc3 | Psc3 | SA1/STAG1,SA2/STAG2 |
Cohesin regulators | Scc2 | Mis4 | NIPBL |
| Â | Scc4 | Ssl3 | MAU2/Scc4 |
| Â | Eco1/Ctf7 | Eso1 | EFO1/ESCO1,EFO2/ESCO2 |
| Â | Pds5 | Pds5 | Pds5A, Pds5B |
| Â | Rad61 | Wpl1 | Wapl |
| Â | - | - | Sororin |
Condensins | Smc2 (I&II) | Cut14 | CAP-E |
| Â | Smc4 (I&II) | Cut3 | CAP-C |
| Â | Brn1 | Cnd2 | CAP-H (I) |
| Â | Ycs4 | Cnd1 | CAP-D2 (I) |
| Â | Ycs5 | Cnd3 | CAP-G (I) |
| Â | - | - | CAP-D3 (II) |
| Â | - | - | CAP-G2 (II) |
| Â | - | - | CAP-H2 (II) |
The Smc5/6 complex | Smc5 | Spr18/Smc5 | Smc5 |
| Â | Rhc18/Smc6 | Rad18/Smc6 | Smc6 |
| Â | Nse1 | Nse1 | Nse1 |
| Â | Mms21/Nse2 | Nse2 | Nse2 |
| Â | YDR228W/Nse3 | Nse3 | Nse3 |
| Â | Qri2/Nse4 | Rad62/Nse4 | Nse4 |
| Â | YML023C/Nse5 | Nse5 | - |
| Â | Kre29/Nse6 | Nse6 | - |