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Table 7 Top ten up- and down- regulated novel isoforms expressed only in normal synovial RNA or rheumatoid arthritis synovial RNA

From: RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis

Gene Description Coordinates Length FPKM Wildtype FPKM RA Ensembl gene ID
GIPC1 GIPC PDZ domain containing family. Member 1 chr19:14588570-14606944 1650 -- 8.09135 ENSG00000123159
MPPE1 Metallophosphoesterase 1 chr18:11883385-11908455 1973 -- 5.66007 ENSG00000154889
- NA chr11:69066649-69184402 410 -- 5.19725 NA
EPB41L2 Erythrocyte membrane protein band 4.1-like 2 chr6:131160487-131384462 3393 -- 4.45046 ENSG00000079819
MRPL14 Mitochondrial ribosomal protein L14 chr6:44072507-44123256 658 -- 4.29538 ENSG00000180992
PPIEL Peptidylprolyl isomerase E-like pseudogene chr1:39987953-40025316 509 -- 4.21536 ENSG00000243970
- NA chr6:166822859-167041186 3525 -- 3.83632 NA
- NA chr21:39607975-39679370 1369 -- 3.3631 NA
FAM101A Family with sequence similarity 101. member A chr12:124774147-124800566 2242 -- 3.16322 ENSG00000178882
- NA chr4:39454172-39460535 666 -- 3.12642 NA
- NA chr20:30432079-30433458 1379 18.1953 -- NA
GPAT2 Glycerol-3-phosphate acyltransferase 2, mitochondrial chr2:96687342-96700658 2732 6.12103 -- ENSG00000186281
PCDHGC5 Protocadherin gamma subfamily C, 5 chr5:140746308-140914003 4930 6.08509 -- ENSG00000240764
RSAD2 Radical S-adenosyl methionine domain containing 2 chr2:6988770-7038095 5210 4.87066 -- ENSG00000134321
HEYL Hairy/enhancer of split related with YRPW motif-like chr1:40089102-40105348 3872 4.34476 -- ENSG00000163909
GPR107 G protein-coupled receptor 107 chr9:132815745-132902440 3463 4.15184 -- ENSG00000148358
GOLGA2 Golgin A2 chr9:131018105-131038268 3014 2.8846 -- ENSG00000167110
HHIP Hedgehog interacting protein chr4:145567142-145660251 2628 2.57248 -- ENSG00000164161
ITIH3 Inter-alpha-trypsin inhibitor heavy chain 3 chr3:52828743-52838029 1944 2.20862 -- ENSG00000162267
HEATR5A HEAT repeat containing 5A chr14:31757730-31889797 6427 2.17675 -- ENSG00000129493
  1. Novel isoforms which were differentially expressed as determined by CuffDiff after Benjamini-Hochberg correction. The isoforms were ranked by FPKM and the 10 with the highest or lowest fold changes are listed here.