Table 11 Top canonical pathways affected by up-regulated genes/isoforms in rheumatoid arthritis synovial RNA
From: RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis
| Â | Up-regulated genes | Â |
|---|---|---|
Canonical Pathway | p-value | Ratio |
Antigen Presentation Pathway | 0.000 | 0.455 |
Graft-versus-Host Disease Signaling | 0.000 | 0.275 |
Communication between Innate and Adaptive Immune Cells | 0.000 | 0.188 |
Crosstalk between Dendritic Cells and Natural Killer Cells | 0.000 | 0.159 |
Autoimmune Thyroid Disease Signaling | 0.000 | 0.214 |
| Â | Up-regulated Isoforms | Â |
Canonical Pathway | p-value | Ratio |
Atherosclerosis Signaling | 0.001 | 0.133 |
Hepatic Fibrosis / Hepatic Stellate Cell Activation | 0.001 | 0.119 |
Colorectal Cancer Metastasis Signaling | 0.010 | 0.088 |
Toll-like Receptor Signaling | 0.011 | 0.143 |
FXR/RXR Activation | 0.012 | 0.114 |