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Figure 5 | Cell & Bioscience

Figure 5

From: GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation

Figure 5

Expression of PPARβ/δ and PPARβ/δ-dependent genes in LX-2 human hepatic stellate cells. Human LX-2 stellate cells were serum-starved for 24 h, and then treated with DMSO (0.01%), 100nM GW501516, or 1μM GW501516 for 48 h. qRT-PCR analysis shows mRNA levels of PDPK1, TGF β1, TNF- α, MCP-1, Pro-COL1 α1, Pro-COL3 α1 and Desmin. Results are means ± SD of at least three independent experiments performed in triplicate. * = p<0.05, Student's t-test.

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