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Table 1 Classification of nuclear hormone receptors

From: Nuclear hormone receptors in podocytes

Class Nuclear Receptor Abbreviation Hormones and Synthetic Ligands
I Androgen receptor AR testosterone, flutamide
Estrogen receptor, alpha and beta ERα, β estrogens, tamoxifen, raloxifene
Glucocorticoid receptor GR glucocorticoidl, dexamethasone, RU486
Mineralocorticoid receptor MR aldosterone, spirolactone
Progesterone receptor PR progesterone, medroxyprogesterone acetate, RU486
II Constitutive and rostane receptor CAR androstane
Farnesoid X receptor FXR bile acids, Fexaramine
Liver X receptor, alpha and beta LXRα, β oxysterols, T0901317, GW3965
Peroxisome proliferator-activated receptor alpha PPARα fibrates
Peroxisome proliferator-activated receptor beta/delta PPARβ/δ fatty acids
Peroxisome proliferator-activated receptor gamma PPARγ prostaglandins
Pregnane X receptor PXR xenobiotics
Retinoid A receptor, alpha, beta and gamma RARα, β, γ all-trans retinoic acid
Thyroid hormone receptor, alpha and beta TRα, β, γ thyroid hormone
Vitamin D receptor VDR vitamin D
III Chicken ovalbumin upstream promoter-transcription factor I COUP-TFI n/a
Chicken ovalbumin upstream promoter-transcription factor II COUP-TFII n/a
V-erbA-related receptor EAR-2 n/a
Germ cell nuclear factor GCNF n/a
Hepatocyte nuclear factor-4, alpha and gamma HNF4α, γ Fatty acids
Photoreceptor cell-specific nuclear receptor PNR 9-cis retinoic acids
Retinoid X receptor, alpha, beta and gamma RXRα, β, γ 9-cis retinoic acids
Testicular receptor 2 TR2 n/a
Testicular receptor 4 TR4 n/a
Homologue of the Drosophila tailless gene TLX n/a
IV Estrogen-related receptor alpha, beta and gamma ERRα, β, γ 9-cis retinoic acid
Liver receptor homolog-1 LRH-1 phosphatidylinositols
Nerve Growth factor IB NGFIB n/a
Neuron-derived orphan receptor 1 NOR1 N/As
Nuclear receptor related 1 NURR1 N/A
Rev-ErbA, alpha and beta Rev-Erbα, β heme
RAR-related orphan receptor, alpha, beta and gamma RORα, β, γ cholesterol, all-trans retinoic acids
Steroidogenic factor 1 SF1 phosphatidylinositols
Dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene DAX n/a
  Small heterodimer partner SHP n/a
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