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Figure 1 | Cell & Bioscience

Figure 1

From: Effects of HIV-1 protease on cellular functions and their potential applications in antiretroviral therapy

Figure 1

Life cycle of the HIV-1. Life cycle of HIV-1 occurs in 6 major steps: 1) adsorption and fusion of viral particle, 2) reverse transcription by Reverse Transcriptase, 3) integration of viral dsDNA into genomic DNA by Integrase, 4) expression of viral genes, 5) cleavage of Gag-pol and Gag precursor by HIV-1 PR and assembly of proteins into mature viral particle, and 6) budding of mature virion from host cell.

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