Figure 3
From: PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease
Increased severity of adoptive transfer EAE in recipients of PDLIM2 deficient CD4+T cells. CD4+ T cells were isolated from PDLIM2+/+ and PDLIM2−/− mice immunized with PLP180–199 peptide and transferred i.v. into SCID recipients (n = 20). One day after the cell transfer, recipient mice also received an injection of pertussis. Mice were then monitored for the symptoms of EAE as described in Figure .2