Figure 2From: PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune diseaseIncreased susceptibility to EAE in PDLIM2 deficient mice. A) Incidence, B) disease progression, C) severity and D) onset of EAE in PDLIM2+/+ and PDLIM2−/− mice (n = 15). Mice were immunized with PLP180–199 peptide and monitored daily for EAE disease symptoms. The p values between the PDLIM2+/+ (WT) and PDLIM2−/− (KO) groups are at least smaller than 0.05 by two tailed t-test.Back to article page