Figure 1
From: PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease
Enhanced Th1 and Th17 differentiation of PDLIM2 deficient CD4+Th cells. Naive CD4+ Th cells isolated from PDLIM2+/+ (WT) or PDLIM2−/− (KO) mice were stimulated for 72 hours with anti-CD3/anti-CD28 under Th1, Th2, Th17 or Treg polarizing condition, followed by intracellular cytokine staining and flow cytometry. The data are representative of at least three independent experiments with similar results.