Table 1 Combined injury signs compared to radiation injury signs
From: Wound trauma alters ionizing radiation dose assessment
Early signs | More water intake |
Greater decreases in numbers of total WBCs | |
More γ-H2AX formation in Lin+ bone-marrow cells | |
Similar decreases in survivin protein | |
Increased serum concentrations of IL-1β, -6, -8, G-CSF, and Flt-3 ligand | |
Intermediate signs | Faster body-weight decreases |
Slower wound-healing rate | |
Greater decreases in numbers of RBCs and platelets | |
Less γ-H2AX formation in PBMCs | |
Greater increases in serum concentrations of IL-1β, -6, -8, and G-CSF | |
Late signs | Sustained elevated serum concentrations of IL-8 and G-CSF |
More mortality | |
Slower wound-healing rate |