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Table 1 Mean size (μm) of DIG-dUTP incorporation signals in nuclei of hamster and mouse cells in the presence or absence of Tax or etoposide

From: Unstabilized DNA breaks in HTLV-1 Tax expressing cells correlate with functional targeting of Ku80, not PKcs, XRCC4, or H2AX

Experimental groups n mean size Standard deviation
1 Mouse embryo fibroblasts (MEFs) 68 1.37 0.46
2 MEFs + etoposide 5 μg/ml * 46 1.77 1.15
3 MEFs + etoposide 10 μg/ml * 50 2.06 0.96
4 CHO 66 1.16 0,31
5 CHO + Tax 50 3.81 1.74
6 xrs-6 56 1.99 0.82
7 xrs-6 + Tax 120 2.08 0.67
8 PKcs+/+ 38 1.43 0.51
9 PKcs+/+ + Tax 70 2.28 1.05
10 PKcs−/− 98 1.35 0.45
11 PKcs−/− + Tax 150 2.35 0.99
12 XRCC4+/+ 77 1.63 0.69
13 XRCC4+/+ + Tax 50 3.53 1.68
14 XRCC4−/− 175 1.74 0.67
15 XRCC4−/− + Tax 48 3.39 1.12
16 H2AX+/+ 68 1.37 0.46
17 H2AX+/+ + Tax 70 2.50 0.95
18 H2AX−/− 65 2.01 0.76
19 H2AX−/− + Tax 68 3.20 0.90
  1. * = three hours of treatment.
  2. n = number of measured DIG-dUTP incorporation signals.
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