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Table 1 Functional categories of the TRBP-associated complex

From: A proteomic study of TAR-RNA binding protein (TRBP)-associated factors

Category

Molecules

Protein Synthesis

ABCF1, EEF1A2, EIF2AK2, EIF2S1, PTBP1, RPL3, RPL4, RPL5, RPL6, RPL7, RPL9, RPL11, RPL15, RPL18, RPL21, RPL22, RPL24, RPL30, RPL32, RPL34, RPL35, RPL18A, RPL23A, RPL27A, RPL29 (includes EG:6159), RPL31 (includes EG:6160), RPL7A (includes EG:6130), RPS2, RPS5, RPS6, RPS9, RPS10, RPS11, RPS17 (includes EG:6218), RPS3A

RNA Post-Transcriptional Modification

DDX17, DDX54, EFTUD2, HNRPAB, HNRPC, HNRPUL1, PABPC1, PRPF8, PTBP1, SFRS1, SNRPD1, SNRPD3, SYNCRIP, U2AF1

Cellular Growth and Proliferation

AKAP13, ATP5B, ATP5F1, CCT2, DBN1, DCD, DNAJA3, EIF2AK2, GLTSCR2, HMGA1, HNRPA1, HNRPAB, HNRPC, HNRPF, HNRPM, PHB (includes EG:5245), PPP1R9B, PRPF8, PRPF19, RAP1B, RPS3A, RSL1D1, SART1, SFRS1, TOP1, XRN2

Gene Expression

BASP1, BTF3, CDC5L, CHD4, CSDA, DDX5, DEK, EIF2S1, GTF3C1, GTF3C3, GTF3C4, HMGA1, HNRPAB, IGHMBP2, PARP1, PHB (includes EG:5245), RBM39, RPL6, SOX21, TARBP2, TOP1, TOP2A

Cell Death

DDX5, DIDO1, DNAJA3, EEF1A2, EIF2AK2, EIF2S1, GNL3, HIST1H1C, HMGA1, HNRPA1, HNRPC, HSPA1B, PARP1, PHB (includes EG:5245), PPP1R9B, PRPF19, RBBP4, RPLP0 (includes EG:6175), RPS3A, SLC2A1, TOP1, TOP2A

DNA Replication, Recombination, and Repair

CDC5L, HMGA1, HSPA1B, IGHMBP2, PARP1, PRPF19, TOP1, TOP2A

Cell Cycle

CDC5L, EIF2AK2, GNL3, HMGA1, NOL1, PARP1, PES1, PHB (includes EG:5245), PPP1R9B, PRMT5, RPL5, RPL11, RPL23, TOP2A

Cancer

RPL5, RPL11, RPL23, AKAP13, ASPH, DNAJA3, HMGA1, HSPA1B, PES1, PRMT5, RPS3A

Skeletal and Muscular Disorders

RPL5, RPL11, RPL23

Cell Morphology

AKAP13, ASPH, DNAJA3, HMGA1, HSPA1B, PES1, PRMT5, RPS3A

Cellular Function and Maintenance/Connective Tissue Development and Function

EIF2AK2, EIF2S1

Viral Function

AKAP13, EIF2AK2, HMGA1, PARP1, SFRS1