Morphologic appearances of LEF2 tumor xenografts. A) Comparison of parental renal cell tumor from an Eker rat and a LEF2 xenograft. Shown are representative sections of H&E-stained, formalin-fixed tumors. Magnification 400×. B) Representative microscopic appearances of the LEF2 xenografts at time of sacrifice from each treatment group. Shown are low- (left) and high- (right) magnification views of the H&E and BrdU staining for each of the 4 treatment groups. Note the hemorrhagic and necrotic zones (arrows) in the Carb-free sample.