Systemic metabolic responses to diets and 2-DG. Sera obtained at sacrifice in fasted animals was analyzed for A) glucose, B) β-hydroxybutyrate (BHOB), C) insulin and D) triglyceride (TG). Chronic diet (black bars) indicates those that were treated for 14 weeks. Acute diet (open bars) indicates treatments for 4 days. Error bars represent SEM. *, p < 0.05.