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Figure 2 | Cell & Bioscience

Figure 2

From: Distinct biological effects of different nanoparticles commonly used in cosmetics and medicine coatings

Figure 2

Treatment with zinc oxide nanoparticles led to caspase-independent cell death. HT29-SCAT3 cells were treated with 0.1% DMSO (vehicle; negative control), ZnO (10 μg/ml), TiO2 (30 μg/ml), FeO (30 μg/ml) and staurosporine (1 μM; positive control) for 18 hrs. The images were collected by an automated high-throughput microscope with a 20× objective (ImageXpress Micro). The addition of a caspase inhibitor IDN6556 (10 μM) did not inhibit cell death induced by ZnO. This experiment was repeated 3 times.

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