General metabolism of Laribacter hongkongensis: a genome-wide analysis

Cell & Bioscience

Table 6 Comparison of sulfur metabolism deduced from the genomes of L. hongkongensis, N. meningitidis, N. gonorrhoeae, C. violaceum, E. coli and C. jejuni

Pathway/enzyme	Gene(s)	*L. hongkongensis* HLHK9	*C. violaceum* ATCC 12472	*N. gonorrhoeae* FA 1090	*N. meningitidis* MC58	*E. coli* K12 MG1655	*C. jejuni* NCTC 11168
Sulfate assimilation
sulfate adenylyltransferase	cysD, cysN	+	+	-	+	+	+
APS kinase	cysC	-	+	-	-	+	+
PAPS reductase	cysH ^a	-	?^b	-	-	+	-
APS reductase	cysH ^a	+	?^b	-	+	-	-
Sulfite reductase	cysI, cysJ	+	+	+	+	+	-
Sulfate transport
ATP binding protein CysA	cysA	+	+	+	+	+	-
Permease protein CysU	cysU	+	+	+	+	+	-
Permease protein CysW	cysW	+	+	+	+	+	-
Sulfate binding protein CysP	cysP	+	+	+	+	+	-

^aBacterial PAPS reductase and APS reductase are highly homologous and both of their gene designation are cysH which may represent a PAPS reductase or APS reductase [58].
^bPredicted amino acid sequences encoded by cysH (CV_3574) in C. violaceum has the characteristic two-cysteine motifs of APS reductase and the presence of cysC suggests an ambiguity (represent by "?") in the identity of CV_3574 as PAPS or APS reductase.

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