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Table 1 List of DNA inserts from screen colonies

From: Systematic analysis of secreted proteins reveals synergism between IL6 and other proteins in soft agar growth of MCF10A cells

total inserts % of all inserts protein Protein family Description Role in Breast cancer
68 6.9% WFDC13 WFDC WAP Four-Disulfide Core Domain 13 no
36 3.6% PON1 PON Paraoxonase 1 no
31 3.1% Wnt3 Wnt Wingless-type MMTV Integration Site Family, Member 3 [7]
18 1.8% FGFBP2 FGFBP Fibroblast Growth Factor Binding Protein 2 no
15 1.5% IL6 Interleukin Interleukin 6 (Interferon, Beta 2) [10]
15 1.5% FGF14 FGF Fibroblast Growth Factor 14 no
14 1.4% SAA1 SAA Serum Amyloid A1 [24]
14 1.4% PTHLH PTHLH Parathyroid Hormone-Like Hormone [23]
13 1.3% FGF10 FGF Fibroblast Growth Factor 10 [6]
12 1.2% LYNX1 Ly-6 Ly6/Neurotoxin 1 No
12 1.2% IL21 Interleukin Interleukin 21 Refs in [38]
11 1.1% IL22 Interleukin Interleukin 22 [16]
10 1.0% WFDC14 WFDC Peptidase Inhibitor 3, Skin-Derived (SKALP) no
10 1.0% SUMF1 SUMF Sulfatase Modifying Factor 1 no
10 1.0% FGF1 FGF Fibroblast Growth Factor 1 (acidic) [22]
  1. The most recurrent DNA inserts recovered from screen colonies are listed, with indication of the protein family they belong to, and publications linking the proteins to breast cancer development.