Fig. 2
From: Interruptible demyelination in avian riboflavin deficient neuropathy
Light micrographs, P1 and P3; Electron micrographs, P2 and P4. P1 is part of a TF from a VB2−/+PH14d chicken displaying paranodal and partial internodal demyelination according to the surface appearance. P2 is a longitudinal section through the paranodal demyelination segment. A Schwann cell nucleus (SN) is present. This Schwann cell envelops the axon under basal lamella of the nerve fibre (inserts). P3 left is a longitudinal section through the middle of the neighbouring myelin-maintained segment showing a Schwann cell nucleus (SN), 2 attached fibroblasts (Fi) and myelin debris (white arrows). P3 right is a longitudinal section through the partial internodal demyelination segment. A centrally located Schwann cell nucleus (SN) is present. Redundant myelin foldings with myelin breakdown (white arrows) is present in the paranodal region of the neighbouring myelin-maintained segment. P4 is a longitudinal section (rotate 90°) through the partial internodal demyelination region (arrowhead in panel 1) showing 4 layers of non-compacted myelin lamellae surrounding the axon under the basal lamella of the nerve fibre: an inner mesaxon (white arrowhead) connecting the axolemma and outer mesaxon (double white arrowheads) connecting Schwann cell basement membrane