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Table 3 The association between Klotho and all-cause mortality in CKD population

From: Klotho exerts protection in chronic kidney disease associated with regulating inflammatory response and lipid metabolism

Klotho

CKD population

Unadjusted model

Adjusted model

HR (95% CI)

P-value

HR (95% CI)

P-value

T1

Ref.

   

T2

0.827 (0.589, 1.161)

0.272

0.828 (0.601, 1.142)

0.249

T3

0.685 (0.506, 0.927)

0.014

0.711 (0.483, 1.048)

0.085

P–t

 

0.016

 

0.088

Continuous

0.933 (0.891, 0.976)

0.003

0.942 (0.890, 0.997)

0.039

  1. The unadjusted model was not adjusted by any covariates. The adjusted model was fully adjusted for sex, age, race, educational attainment
  2. BMI, smoking status, CVD, DM and hypertension. HR, hazard ratio; CI, confidence interval; P–t, P for trend; T1, the lowest tertile of Klotho level; T2, the moderate tertile of Klotho level; T3, the highest tertile of Klotho level; Ref, reference