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Fig. 2 | Cell & Bioscience

Fig. 2

From: Unveiling the functional heterogeneity of cytokine-primed human umbilical cord mesenchymal stem cells through single-cell RNA sequencing

Fig. 2

Predicted functions and pathways associated with DEGs after cytokine priming in hUC-MSCs. (A) Differential expression gene analysis showing upregulated and downregulated genes across cytokine-primed hUC-MSCs. An adjusted p value < 0.01 is indicated in red, while an adjusted p value > = 0.01 is indicated in gray. (B) Statistical table of genes significantly differentially expressed between cytokine-primed hUC-MSCs and unprimed hUC-MSCs. (C-D) KEGG (C) and GO (D) enrichment analyses of IFN-γ-, TNF-α-, or IL-4-primed hUC-MSCs; dot plot showing the most significant terms. The size of each dot indicates the gene ratio (the total number of DEG-enriched genes). The color indicates the adjusted p value for enrichment analysis. (E) GO enrichment network of IFN-γ-primed hUC-MSCs. (F) GO enrichment network of TNF-α-primed hUC-MSCs. (G) GO enrichment network of IL-4-primed hUC-MSCs

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Cell & Bioscience

ISSN: 2045-3701

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