Fig. 2
From: The role of long noncoding RNAs in ocular angiogenesis and vascular oculopathy
Cytoplasmic mechanisms of LncRNAs. A) LncRNAs can interact with 3’-untranslated region (UTR) binding proteins which impact mRNA stability. B) Antisense lncRNAs regulate mRNA stability by forming duplexes with mRNA through complementary base pairing C) LncRNAs can have microRNA (miRNA)-complementary sites that act as competitive endogenous RNAs (ceRNAs) and sequester miRNAs away from their targets D) LncRNAs regulate protein translation and affect post-translational mechanisms. E) LncRNAs code for regulatory micro-peptides. F) LncRNAs regulate signaling pathways in the cytoplasm