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Fig. 5 | Cell & Bioscience

Fig. 5

From: Membrane-associated RING-CH 7 inhibits stem-like capacities of bladder cancer cells by interacting with nucleotide-binding oligomerization domain containing 1

Fig. 5

E3 enzyme activity was required for the inhibitory effect of MARCH7 on cancer stem cells evidenced by in vivo model. A Volume change of tumor growth. B Changes in tumor weight. C Photograph of the tumors. D Western blot detected the effects of MARCH7 on NOD1 protein levels in the tumors of nude mice. E Cancer cell stemness-, proliferation-, invasion- and metastasis-, and apoptosis-related gene expression in xenograft tissues evidenced by q-PCR analysis. Here, *p < 0.01 vs. Vector group, #p < 0.01 vs. MARCH7-WT group. All experiments were conducted in triplicate, and each assay was repeated 3 times independently

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Cell & Bioscience

ISSN: 2045-3701

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