Single nuclear RNA sequencing of terminal ileum in patients with cirrhosis demonstrates multi-faceted alterations in the intestinal barrier

Table 1 Major changes in individual cell types in different disease stages.

	Advanced decompensation		Early decompensation		Compensated cirrhosis		Control
	Count	Percent (%)	Count	Percent (%)	Count	Percent ()%)	Count	Percent (%)
Endothelial cell	61	2.01	27	0.88	5	0.20	34	1.25
Enterocyte 1	339	11.18	473	15.44	579	22.77	294	10.84
Enterocyte 2	123	4.06	245	8.00	464	18.25	306	11.29
Enterocyte 3	5	0.16	156	5.09	679	26.70	78	2.88
Enteroendocrine cell	47	1.55	20	0.65	26	1.02	32	1.18
Goblet cell	53	1.75	111	3.62	174	6.84	97	3.58
Lym 1	422	13.92	71	2.32	38	1.49	186	6.86
Lym 2	326	10.75	58	1.89	58	2.28	127	4.68
Microfold cell	27	0.89	14	0.46	28	1.10	29	1.07
Neuron	151	4.98	1070	34.92	20	0.79	183	6.75
Neuron 2	26	0.86	329	10.74	51	2.01	141	5.20
Paneth cell	557	18.37	148	4.83	214	8.42	215	7.93
Stem cell	47	1.55	155	5.06	146	5.74	584	21.54
TA	848	27.97	187	6.10	61	2.40	405	14.94
Total	3032	100.00	3064	100.00	2543	100.00	2711	100.00tata

ISSN: 2045-3701