Skip to main content
Fig. 5 | Cell & Bioscience

Fig. 5

From: Single nuclear RNA sequencing of terminal ileum in patients with cirrhosis demonstrates multi-faceted alterations in the intestinal barrier

Fig. 5

IPA Analysis Results for Enterocyte-Specific Differential Gene Expressions for (A) Compensated vs Healthy Control, (B) Early Decompensated vs Healthy Control and (C) Advanced Decompensated vs Healthy Control. The pathway maps show the potential interactions between major transcription factors, pathways, and biological functions that were differentially expressed or predicted to be regulated. Orange represents upregulation and blue represents downregulation. Numerous regulated pathways can be observed in these pathway maps. A notable pattern is the upregulation of inflammation and immune faction related pathways in all three samples as compared the healthy control, including TNF and IFNG in A, IFNA2 in B, and IFNG, IL6, IL1B in C

Back to article page

Cell & Bioscience

ISSN: 2045-3701

Contact us