Table 1 Drugs targeting PFKFB3
From: PFKFB3 in neovascular eye disease: unraveling mechanisms and exploring therapeutic strategies
Drug name | Clinical Status | Manufacturer | Current study |
|---|---|---|---|
3PO | Preclinical | Advanced Cancer Therapeutics University of Louisville | [66] |
PFK-15 | Preclinical | Advanced Cancer Therapeutics University of Louisville | [106] |
Phenoxyindole | Preclinical | AstraZeneca | [124] |
AZ-67 | Preclinical | Zhejiang University (Originator) | [125] |
PFK-158 | Phase I - NCT02044861 | Advanced Cancer Therapeutics University of Louisville | [128] |