Fig. 1
From: XBP1-mediated transcriptional regulation of SLC5A1 in human epithelial cells in disease conditions
SGLT1 is upregulated in CF patient-derived airway lineage cells. (A) Representative gel of Western blot (WB) of SGLT1 and CFTR in the CFBE-WT cells and the CFBE-dF cells. (B) Quantification of WB data for the protein levels of SGLT1 in CFBE-WT cells and the CFBE-dF cells. (C) RT-qPCR of SLC5A1 in the CFBE-WT cells and the CFBE-dF cells. (D) Western blot of SGLT1 in CF patient-derived airway epithelial cells. HC-1 and − 2: healthy control; CF-1 and − 2: CF patients of homozygous dF508 mutation. (E) Immunofluorescence staining of SGLT1 in the CFBE-WT cells and the CFBE-dF cells. Scale bar: 20 μm